曹艳，特聘副研究员。南京工业大学博士，美国罗德岛大学博士后，曾就职于金斯瑞生物科技有限公司、上海细胞治疗集团等知名生物医药企业；曾主持抗CD47单克隆抗体、间皮素CAR-T等多个创新药物的IND项目开发与申报工作，并成功获得临床试验批件；擅长抗体筛选、功能改造及体内外药效评价；具备从抗体早期发现到CMC、再到注册申报的全流程项目管理经验，致力于推动创新免疫治疗与生物药物的临床转化。

治疗性抗体药物开发及药效评价；新型药物递送系统的开发

科研论文

1. Yan Cao, Xiaoyue Zhu, Md. NazirHossen, Prateek Kakar, Yiwen Zhao, Xinyuan Chen*. Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant. Nat. Commun. 9 (2018) 3695.

2. Yan Cao, Prateek Kakar, Md. NazirHossen, Mei X.Wu, Xinyuan Chen*. Sustained epidermal powder drug delivery via skin microchannels. J. Control. Release. 249 (2017) 94-102.  

3. Yan Cao, Huan Yang, Xiaolong Zhou, Huiwen Mao, Tingting Gao, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo*. Selection and Characterization of Human PCSK9 Antibody from Phage Displayed Antibody Library. Biochem. Bioph. Res. Co. 463(2015)712-718.

发明专利

1. 郭志刚，曹艳，高婷婷，杨欢. 针对PCSK9的全人源单克隆抗体的可变区基因及其应用. (ZL 201510205553.5)

治疗性抗体药物开发及药效评价；新型药物递送系统的开发

科研论文

1. Yan Cao, Xiaoyue Zhu, Md. NazirHossen, Prateek Kakar, Yiwen Zhao, Xinyuan Chen*. Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant. Nat. Commun. 9 (2018) 3695.

2. Yan Cao, Prateek Kakar, Md. NazirHossen, Mei X.Wu, Xinyuan Chen*. Sustained epidermal powder drug delivery via skin microchannels. J. Control. Release. 249 (2017) 94-102.  

3. Yan Cao, Huan Yang, Xiaolong Zhou, Huiwen Mao, Tingting Gao, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo*. Selection and Characterization of Human PCSK9 Antibody from Phage Displayed Antibody Library. Biochem. Bioph. Res. Co. 463(2015)712-718.

发明专利

1. 郭志刚，曹艳，高婷婷，杨欢. 针对PCSK9的全人源单克隆抗体的可变区基因及其应用. (ZL 201510205553.5)